Agonistas del receptor de GLP-1
نویسندگان
چکیده
منابع مشابه
Peptide binding at the GLP-1 receptor.
The receptor for GLP-1 [glucagon-like peptide-1-(7-36)-amide] is a member of the 'Family B' of GPCRs (G-protein-coupled receptors) comprising an extracellular N-terminal domain containing six conserved cysteine residues (the N-domain) and a core domain (or J-domain) comprising the seven transmembrane helices and interconnecting loop regions. According to the two-domain model for peptide binding...
متن کاملGLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance
BACKGROUND/OBJECTIVES Fasting dyslipidemia is commonly observed in insulin resistant states and mechanistically linked to hepatic overproduction of very low density lipoprotein (VLDL). Recently, the incretin hormone glucagon-like peptide-1 (GLP-1) has been implicated in ameliorating dyslipidemia associated with insulin resistance and reducing hepatic lipid stores. Given that hepatic VLDL produc...
متن کاملEstudio Preliminar De Los Polimorfismos Del Gen Grin-1 Del Receptor Nmda En Una Población Sana Colombiana
It is well known that the gene GRIN-1 plays a fundamental role in many cerebral functions and it has been associated with numerous diseases. For this reason it has awakened a great scientific interest in understanding how the polymorphisms of this gene are distributed among normal and diseased populations. Up to now the polymorphisms that lead to an amino acid change in the protein have not bee...
متن کاملSolución Numérica del Problema de Control de Contaminación del Aire
This work presents a stochastic outer approximation algorithm to solve air pollution control problem while minimizing the control costs which thereby occur. These air quality standards give rise to an infinite number of constraints and this is a semi-infinite programming problem.
متن کاملPurslane Effect on GLP-1 and GLP-1 receptor in type 2 diabetes
BACKGROUND The aim of this study was to examine the effect of purslane seeds in glucagon-like peptide-1 concentration and glucagon-like peptide-1 receptor in women with diabetes. METHODS This was a quasi-experimental study. The population was consisted of the city of Sari where diabetic women with diabetes II who had no history of using purslane seeds. All individuals used the same dose of me...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Diagnóstico
سال: 2020
ISSN: 1018-2888
DOI: 10.33734/diagnostico.v59i2.219